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Western blot analysis of extracts from mouse brain cells, using PPP1R16B antibody P42533.

Rabbit Polyclonal Antibody to PPP1R16B

  • 货号:

    P42533
  • 别名:

    TGF-beta-inhibited membrane-associated protein; hTIMAP; CAAX box protein TIMAP; Ankyrin repeat domain-containing protein 4;
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB
  • 反应种属:

    Human,Mouse
  • 抗体类型:

    Primary antibody
  • Swissprot:

    Q96T49
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥1980

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Rabbit Polyclonal Antibody to PPP1R16B

Description

Regulator of protein phosphatase 1 (PP1) that acts as a positive regulator of pulmonary endothelial cell (EC) barrier function. Involved in PKA-mediated moesin dephosphorylation which is important in EC barrier protection against thrombin stimulation. Promotes the interaction of PPP1CA with RPSA/LAMR1 and in turn facilitates the dephosphorylation of RPSA/LAMR1. Involved in the regulation of endothelial cell filopodia extension. May be a downstream target for TGF-beta1 signaling cascade in endothelial cells.Cao W., Am. J. Physiol. 283:C327-C337(2002).Nagase T., DNA Res. 5:355-364(1998).Nakajima D., DNA Res. 9:99-106(2002).

Specification

Aliases TGF-beta-inhibited membrane-associated protein; hTIMAP; CAAX box protein TIMAP; Ankyrin repeat domain-containing protein 4;
Entrez GeneID 26051;
Swissprot Q96T49
WB Predicted band size 64kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse
Immunogen Synthesized peptide derived from internal of human PPP1R16B.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/3000

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#P42533

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