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Western blot analysis of extracts from 293 cells, transfected with Tau and treated with calf intestinal phosphatase (CIP) using Tau(Phospho-Thr181) Rabbit mAb.

Rabbit Monoclonal Antibody to Recombinant Tau(Phospho-Thr181) Rabbit mAb(G69)

  • 货号:

    P43717
  • 别名:

    MAPT; MTAPT; MTBT1; Neurofibrillary tangle protein; PHF-tau
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB
  • 反应种属:

    Human,Mouse,Rat
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P10636
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Rabbit Monoclonal Antibody to Recombinant Tau(Phospho-Thr181) Rabbit mAb(G69)

Description

Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

References

Puig B, et al.(2005) Acta Neuropathol (Berl). 110(3):261-268.

Specification

Aliases MAPT; MTAPT; MTBT1; Neurofibrillary tangle protein; PHF-tau
Swissprot P10636
WB Predicted band size 48 62 78 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat
Immunogen Peptide sequence around phosphorylation site of threonine 181 derived from Human Tau.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/1000

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#P43717

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