Description
SUFU encodes a component of the Sonic hedgehog (SHH; MIM 600725)/Patched (PTCH; MIM 601309) signaling pathway. Mutations in genes encoding components of this pathway are deleterious for normal development and are associated with cancer-predisposing syndromes (e.g., HPE3, MIM 142945; BCNS, MIM 109400; and GCPS, MIM 175700)

References
Zimmern P,et al.(2010) Neurourol Urodyn.29(5):715-8. Wang C,et al. (2010) Development. 137(12):2001-9. Rabasseda X.et al.(2010) Drug News Perspect.23(4):273-5.

Specification
Aliases	SUFUH
Entrez GeneID	51684;
Swissprot	Q9UMX1
WB Predicted band size	54kd
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Peptide sequence around phosphorylation site of Serine 342 (A-P-S(p)-R-K) derived from Human Sufu.
Formulation	Purified antibody in PBS with 0.05% sodium azide.

Application
WB	1/500-1/1000