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Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane 1-3: Hela cell, Mouse fetal brain tissue, Mouse brain tissue lysates, Primary antibody: P00043(YWHAE Antibody) at dilution 1/1000, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 10 seconds
The image is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using P00043(YWHAE Antibody) at dilution 1/70. (Original magnification: ×200)

Rabbit Polyclonal Antibody to YWHAE

  • 货号:

    P00043
  • 别名:

    MDS; HEL2; MDCR; KCIP-1; 14-3-3E
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IHC
  • 反应种属:

    Human, Mouse, Rat
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P62258
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥1980

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Rabbit Polyclonal Antibody to YWHAE

Description

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene.

Specification

Aliases MDS; HEL2; MDCR; KCIP-1; 14-3-3E
Swissprot P62258
WB Predicted band size 29 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse, Rat
Immunogen Fusion protein of human YWHAE
Formulation Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.

Application

WB 1/1000-1/5000
IHC 1/50-1/200
ELISA 1/5000-1/10000
XML 地图