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Gel: 10%SDS-PAGE, Lysate: 60 μg, Lane: Mouse heart tissue, Primary antibody: P00107(APIP Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds

The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P00107(APIP Antibody) at dilution 1/10. (Original magnification: ×200)

Rabbit Polyclonal Antibody to APIP

货号：
P00107
别名：
APIP2, CGI29, CGI-29, MMRP19, dJ179L10.2
产品上架时间：
2024-01-01
应用：
WB,IHC
反应种属：
Human, Mouse
抗体类型：
Primary antibody
Swissprot：
Q96GX9
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to APIP

Description
APIP is an APAF1 (MIM 602233)-interacting protein that acts as a negative regulator of ischemic/hypoxic injury.The protein highly expressed in skeletal muscle and heart and binds to the CARD of Apaf-1 in competition with caspase-9. Exogenous APIP inhibits cytochrome c-induced activation of caspase-3 and caspase-9, and suppresses cell death triggered by mitochondrial apoptotic stimuli through inhibiting the downstream activity of cytochrome c released from mitochondria.

Description

APIP is an APAF1 (MIM 602233)-interacting protein that acts as a negative regulator of ischemic/hypoxic injury.The protein highly expressed in skeletal muscle and heart and binds to the CARD of Apaf-1 in competition with caspase-9. Exogenous APIP inhibits cytochrome c-induced activation of caspase-3 and caspase-9, and suppresses cell death triggered by mitochondrial apoptotic stimuli through inhibiting the downstream activity of cytochrome c released from mitochondria.

Specification
Aliases	APIP2, CGI29, CGI-29, MMRP19, dJ179L10.2
Swissprot	Q96GX9
WB Predicted band size	27 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse
Immunogen	Fusion protein of human APIP
Formulation	Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.