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Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane 1-3: Hela cells, 293T cells, A431 cells, Primary antibody: P00148(APEX1 Antibody) at dilution 1/450, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P00148(APEX1 Antibody) at dilution 1/20. (Original magnification: ×200)

Rabbit Polyclonal Antibody to APEX1

  • 货号:

    P00148
  • 别名:

    APE; APX; APE1; APEN; APEX; HAP1; REF1
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IHC
  • 反应种属:

    Human, Mouse, Rat
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P27695
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥1980

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Rabbit Polyclonal Antibody to APEX1

Description

Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein.

Specification

Aliases APE; APX; APE1; APEN; APEX; HAP1; REF1
Swissprot P27695
WB Predicted band size 36 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse, Rat
Immunogen Fusion protein of human APEX1
Formulation Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.

Application

WB 1/500-1/2000
IHC 1/15-1/50
ELISA 1/2000-1/5000
XML 地图