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Immunohistochemical analysis of paraffin-embedded human cervical carcinoma, showing cytoplasmic localization with DAB staining using KARS mouse mAb.

Mouse Monoclonal Antibody to KARS

  • 货号:

    20238
  • 别名:

    KRS; KARS2; KIAA0070
  • 产品上架时间:

    2024-01-01
  • 应用:

    IHC
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    Q15046
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to KARS

Description

KARS: lysyl-tRNA synthetase. Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis.

References

1. J Biol Chem. 2000 Nov 10;275(45):35063-9.
2. J Virol. 2001 Jun;75(11):5043-8.
3. Biochem Biophys Res Commun. 2002 Feb 15;291(1):158-64.
4. Cell. 2004 Oct 15;119(2):195-208.

Specification

Aliases KRS; KARS2; KIAA0070
Entrez GeneID 3735
Swissprot Q15046
clone 8G12C1
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of KARS(aa90-174) expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.

Application

IHC 1/200 - 1/1000
ELISA 1/10000

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#20238

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