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Rabbit Polyclonal Antibody to CEACAM1
-
货号:
P00263 -
别名:
BGP, BGP1, BGPI -
应用:
WB,IHC -
反应种属:
Human -
抗体类型:
Primary antibody -
Swissprot:
P13688 -
规格:
-
数量:
-+ -
说明书:
目录价¥1980

Rabbit Polyclonal Antibody to CEACAM1
Description |
---|
This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. |
Specification |
|
---|---|
Aliases | BGP, BGP1, BGPI |
Swissprot | P13688 |
WB Predicted band size | 58 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Fusion protein of human CEACAM1 |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
|
---|---|
WB | 1/500-1/2000 |
IHC | 1/15-1/50 |
ELISA | 1/1000-1/5000 |
Product Image
- Gel: 10%SDS-PAGE, Lysate: 60 μg, Lane 1-2: Human liver cancer tissue, Human bladder carcinoma tissue, Primary antibody: P00263(CEACAM1 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes
- The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P00263(CEACAM1 Antibody) at dilution 1/25. (Original magnification: ×200)
- The image is immunohistochemistry of paraffin-embedded Human lung cancer tissue using P00263(CEACAM1 Antibody) at dilution 1/25. (Original magnification: ×200)
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#P00263

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