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Rabbit Polyclonal Antibody to PRKCA
-
货号:
P00631 -
别名:
AAG6; PKCA; PRKACA; PKCI+/-; PKCalpha; PKC-alpha -
应用:
WB,IHC -
反应种属:
Human, Mouse, Rat -
抗体类型:
Primary antibody -
Swissprot:
P17252 -
规格:
-
数量:
-+ -
说明书:
目录价¥1980

Rabbit Polyclonal Antibody to PRKCA
Description |
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Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes. |
Specification |
|
---|---|
Aliases | AAG6; PKCA; PRKACA; PKCI+/-; PKCalpha; PKC-alpha |
Swissprot | P17252 |
WB Predicted band size | 77 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse, Rat |
Immunogen | Fusion protein of human PRKCA |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
|
---|---|
WB | 1/500-1/2000 |
IHC | 1/50-1/200 |
ELISA | 1/5000-1/10000 |
Product Image
- Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: NIH/3T3 and HT-29 cell lysates, Primary antibody: P00631(PRKCA Antibody) at dilution 1/800, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 40 seconds
- The image is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using P00631(PRKCA Antibody) at dilution 1/55. (Original magnification: ×200)
- The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using P00631(PRKCA Antibody) at dilution 1/55. (Original magnification: ×200)
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#P00631

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