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Rabbit Polyclonal Antibody to PLAUR
-
货号:
P00633 -
别名:
CD87; UPAR; URKR; U-PAR -
产品上架时间:
2024-01-01 -
应用:
WB,IHC -
反应种属:
Human -
抗体类型:
Primary antibody -
Swissprot:
Q03405 -
规格:
-
数量:
-+ -
说明书:
目录价¥1980

Rabbit Polyclonal Antibody to PLAUR
Description |
---|
This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. |
Specification |
|
---|---|
Aliases | CD87; UPAR; URKR; U-PAR |
Swissprot | Q03405 |
WB Predicted band size | 37 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Fusion protein of human PLAUR |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
|
---|---|
WB | 1/500-1/2000 |
IHC | 1/50-1/200 |
ELISA | 1/2000-1/5000 |
Product Image
- Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: A549 cells, Primary antibody: P00633(PLAUR Antibody) at dilution 1/450, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
- The image is immunohistochemistry of paraffin-embedded Human lung cancer tissue using P00633(PLAUR Antibody) at dilution 1/60. (Original magnification: ×200)
- The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using P00633(PLAUR Antibody) at dilution 1/60. (Original magnification: ×200)
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#P00633

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