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Rabbit Polyclonal Antibody to ROCK1
-
货号:
P00671 -
别名:
ROCK-I; P160ROCK -
应用:
IHC -
反应种属:
Human, Mouse, Rat -
抗体类型:
Primary antibody -
Swissprot:
Q13464 -
规格:
-
数量:
-+ -
说明书:
目录价¥1980

Rabbit Polyclonal Antibody to ROCK1
Description |
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This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein, a downstream effector of Rho, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. |
Specification |
|
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Aliases | ROCK-I; P160ROCK |
Swissprot | Q13464 |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse, Rat |
Immunogen | Fusion protein of human ROCK1 |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
|
---|---|
IHC | 1/25-1/100 |
ELISA | 1/2000-1/5000 |
Product Image
- The image is immunohistochemistry of paraffin-embedded Human breast cancer tissue using P00671(ROCK1 Antibody) at dilution 1/25. (Original magnification: ×200)
- The image is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using P00671(ROCK1 Antibody) at dilution 1/25. (Original magnification: ×200)
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
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