永利集团-www.304am.com|官方网站-Application program

请登录
搜索 英文站
栏目

提醒成功

请输入手机号/邮箱号
请输入密码

账号密码登录

微信/QQ登录 微信/QQ登录

没有账号? 立即注册

搜索
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-4: 293T cell, Jurkat cell, Mouse brain tissue, LO2 cell lysates, Primary antibody: P00706(SPIN1 Antibody) at dilution 1/1000, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 30 seconds
The image is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using P00706(SPIN1 Antibody) at dilution 1/80. (Original magnification: ×200)
The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P00706(SPIN1 Antibody) at dilution 1/80. (Original magnification: ×200)

Rabbit Polyclonal Antibody to SPIN1

  • 货号:

    P00706
  • 别名:

    SPIN; TDRD24
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IHC
  • 反应种属:

    Human, Mouse, Rat
  • 抗体类型:

    Primary antibody
  • Swissprot:

    Q9Y657
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥1980

加入购物车

Rabbit Polyclonal Antibody to SPIN1

Description

Chromatin reader that specifically recognizes and binds histone H3 both trimethylated at 'Lys-4' and asymmetrically dimethylated at 'Arg-8' (H3K4me3 and H3R8me2a) and acts as an activator of Wnt signaling pathway downstream of PRMT2. In case of cancer, promotes cell cancer proliferation via activation of the Wnt signaling pathway (PubMed:24589551). Overexpression induces metaphase arrest and chromosomal instability. Localizes to active rDNA loci and promotes the expression of rRNA genes (PubMed:21960006). May play a role in cell-cycle regulation during the transition from gamete to embryo. Involved in oocyte meiotic resumption, a process that takes place before ovulation to resume meiosis of oocytes blocked in prophase I: may act by regulating maternal transcripts to control meiotic resumption.

Specification

Aliases SPIN; TDRD24
Swissprot Q9Y657
WB Predicted band size 30 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse, Rat
Immunogen Fusion protein of human SPIN1
Formulation Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.

Application

WB 1/1000-1/5000
IHC 1/50-1/200
ELISA 1/5000-1/10000
XML 地图