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Western blot analysis of lysates from C6 cells, using Rad51 Rabbit mAb. The HRP-conjugated Goat anti-Rabbit IgG antibody (RS0002,immunoway) was used to detect the antibody.

Rabbit Monoclonal Antibody to Rad51

  • 货号:

    50524
  • 别名:

    RAD51;RAD51A;RECA;DNA repair protein RAD51 homolog 1;HsRAD51;hRAD51;RAD51 homolog A
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IF,IP,ELISA
  • 反应种属:

    Human,Mouse,Rat,
  • 抗体类型:

    Primary antibody
  • Swissprot:

    Q06609
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Rabbit Monoclonal Antibody to Rad51

Description

The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009],

Specification

Aliases RAD51;RAD51A;RECA;DNA repair protein RAD51 homolog 1;HsRAD51;hRAD51;RAD51 homolog A
Conjugation Unmodified
Entrez GeneID 5888
Swissprot Q06609
clone 5C9B10
WB Predicted band size 37kD
Host/Isotype Rabbit IgG,Kappa
Antibody Type Primary antibody
Storage -15°C to -25°C/1 year(Do not lower than -25°C)
Species Reactivity Human,Mouse,Rat,
Formulation PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Application

WB 1/1000-1/5000
IP 1/50-1/200
ELISA 1/5000-1/20000

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#50524

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