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Western blot analysis of lysates from Mouse thymus cells, using CD8 α Rabbit mAb. The HRP-conjugated Goat anti-Rabbit IgG antibody (RS0002,immunoway) was used to detect the antibody.

Immunohistochemical analysis of paraffin-embedded human colon tissue. 1, primary Antibody was diluted at 1:200(4～C,overnight). 2, EDTA pH 9.0 was used for antibody retrieval(>98～C,20min). 3,Secondary antibody was diluted at 1:200(room tempeRature, 30min).

Rabbit Monoclonal Antibody to CD8 α

货号：
50544
别名：
T-cell surface glycoprotein CD8 alpha chain;T-lymphocyte differentiation antigen T8/Leu-2;CD antigen CD8a;
产品上架时间：
2024-01-01
应用：
WB,IHC,IF,IP,ELISA
反应种属：
Human,Mouse,Rat,
抗体类型：
Primary antibody
Swissprot：
P01732
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Rabbit Monoclonal Antibody to CD8 α

Description
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011],

Description

The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011],

Specification
Aliases	T-cell surface glycoprotein CD8 alpha chain;T-lymphocyte differentiation antigen T8/Leu-2;CD antigen CD8a;
Conjugation	Unmodified
Entrez GeneID	925
Swissprot	P01732
clone	5G4A10
WB Predicted band size	26kD
Host/Isotype	Rabbit IgG,Kappa
Antibody Type	Primary antibody
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Species Reactivity	Human,Mouse,Rat,
Formulation	PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA