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Rabbit Monoclonal Antibody to SDHB
-
货号:
50742 -
别名:
SDHB;SDH;SDH1;Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial;Iron-sulfur subunit of complex II;Ip -
应用:
WB,IHC,IF,IP,ELISA -
反应种属:
Human,Mouse,Rat, -
抗体类型:
Primary antibody -
Swissprot:
P21912 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180

Rabbit Monoclonal Antibody to SDHB
Description |
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Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis. [provided by RefSeq, Jul 2008], |
Specification |
|
---|---|
Aliases | SDHB;SDH;SDH1;Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial;Iron-sulfur subunit of complex II;Ip |
Conjugation | Unmodified |
Entrez GeneID | 6390 |
Swissprot | P21912 |
clone | 6D3B7 |
WB Predicted band size | 31kD |
Host/Isotype | Rabbit IgG,Kappa |
Antibody Type | Primary antibody |
Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
Species Reactivity | Human,Mouse,Rat, |
Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
Application |
|
---|---|
WB | 1/2000-1/10000 |
IP | 1/50-1/200 |
IHC | 1/200-1/1000 |
ELISA | 1/5000-1/20000 |
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#50742

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