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SH-SY5Y cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with primary antibody 1:1000. The HRP-conjugated Goat anti-Rabbit IgG(H + L) antibody was used to detect the antibody.

Rabbit Monoclonal Antibody to MDR1

  • 货号:

    50790
  • 别名:

    ABC20;ABCB1;ATP binding cassette, sub family B;MDR/TAP;, member 1;ATP-binding cassette sub-family B member 1;CD243;CLCS;Colchicin sensitivity;Doxorubicin resistance;GP170;MDR1;MDR1_HUMAN;Multidrug resistance 1;Multidrug resistance protein 1;P glycoprotein 1;P gp;P-glycoprotein 1;PGY1
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IHC,IF,IP,ELISA
  • 反应种属:

    Human,
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P08183
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Rabbit Monoclonal Antibody to MDR1

Description

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. [provided by RefSeq, Jul 2008],

Specification

Aliases ABC20;ABCB1;ATP binding cassette, sub family B;MDR/TAP;, member 1;ATP-binding cassette sub-family B member 1;CD243;CLCS;Colchicin sensitivity;Doxorubicin resistance;GP170;MDR1;MDR1_HUMAN;Multidrug resistance 1;Multidrug resistance protein 1;P glycoprotein 1;P gp;P-glycoprotein 1;PGY1
Conjugation Unmodified
Entrez GeneID 5243
Swissprot P08183
clone 2D6H3
WB Predicted band size 141kD
Host/Isotype Rabbit IgG,Kappa
Antibody Type Primary antibody
Storage -15°C to -25°C/1 year(Do not lower than -25°C)
Species Reactivity Human,
Formulation PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Application

WB 1/2000-1/10000
IP 1/50-1/200
IHC 1/200-1/1000
ELISA 1/5000-1/20000

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#50790

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