提醒成功

搜索
Rabbit Monoclonal Antibody to MDR1
-
货号:
50790 -
别名:
ABC20;ABCB1;ATP binding cassette, sub family B;MDR/TAP;, member 1;ATP-binding cassette sub-family B member 1;CD243;CLCS;Colchicin sensitivity;Doxorubicin resistance;GP170;MDR1;MDR1_HUMAN;Multidrug resistance 1;Multidrug resistance protein 1;P glycoprotein 1;P gp;P-glycoprotein 1;PGY1 -
应用:
WB,IHC,IF,IP,ELISA -
反应种属:
Human, -
抗体类型:
Primary antibody -
Swissprot:
P08183 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180

Rabbit Monoclonal Antibody to MDR1
Description |
---|
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. [provided by RefSeq, Jul 2008], |
Specification |
|
---|---|
Aliases | ABC20;ABCB1;ATP binding cassette, sub family B;MDR/TAP;, member 1;ATP-binding cassette sub-family B member 1;CD243;CLCS;Colchicin sensitivity;Doxorubicin resistance;GP170;MDR1;MDR1_HUMAN;Multidrug resistance 1;Multidrug resistance protein 1;P glycoprotein 1;P gp;P-glycoprotein 1;PGY1 |
Conjugation | Unmodified |
Entrez GeneID | 5243 |
Swissprot | P08183 |
clone | 2D6H3 |
WB Predicted band size | 141kD |
Host/Isotype | Rabbit IgG,Kappa |
Antibody Type | Primary antibody |
Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
Species Reactivity | Human, |
Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
Application |
|
---|---|
WB | 1/2000-1/10000 |
IP | 1/50-1/200 |
IHC | 1/200-1/1000 |
ELISA | 1/5000-1/20000 |
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#50790

相关产品


