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3T3-L1 cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with primary antibody 1:1000. The HRP-conjugated Goat anti-Rabbit IgG(H + L) antibody was used to detect the antibody.

Rabbit Monoclonal Antibody to XIAP

  • 货号:

    50940
  • 别名:

    XIAP;API3;BIRC4;IAP3;E3 ubiquitin-protein ligase XIAP;Baculoviral IAP repeat-containing protein 4;IAP-like protein;ILP;hILP;Inhibitor of apoptosis protein 3;IAP-3;hIAP-3;hIAP3;X-linked inhibitor of apoptosis protein;X-linked I
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IF,IP,ELISA
  • 反应种属:

    Human,Mouse,Rat
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P98170
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Rabbit Monoclonal Antibody to XIAP

Description

This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.[provided by RefSeq, Feb 2011],

Specification

Aliases XIAP;API3;BIRC4;IAP3;E3 ubiquitin-protein ligase XIAP;Baculoviral IAP repeat-containing protein 4;IAP-like protein;ILP;hILP;Inhibitor of apoptosis protein 3;IAP-3;hIAP-3;hIAP3;X-linked inhibitor of apoptosis protein;X-linked I
Conjugation Unmodified
Entrez GeneID 331
Swissprot P98170
clone 2F8C4
WB Predicted band size 57kD
Host/Isotype Rabbit IgG,Kappa
Antibody Type Primary antibody
Storage -15°C to -25°C/1 year(Do not lower than -25°C)
Species Reactivity Human,Mouse,Rat
Formulation PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Application

WB 1/2000-1/10000
IP 1/50-1/200
ELISA 1/5000-1/20000

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#50940

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