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Rabbit Monoclonal Antibody to XIAP
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货号:
50940 -
别名:
XIAP;API3;BIRC4;IAP3;E3 ubiquitin-protein ligase XIAP;Baculoviral IAP repeat-containing protein 4;IAP-like protein;ILP;hILP;Inhibitor of apoptosis protein 3;IAP-3;hIAP-3;hIAP3;X-linked inhibitor of apoptosis protein;X-linked I -
应用:
WB,IF,IP,ELISA -
反应种属:
Human,Mouse,Rat -
抗体类型:
Primary antibody -
Swissprot:
P98170 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180

Rabbit Monoclonal Antibody to XIAP
Description |
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This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.[provided by RefSeq, Feb 2011], |
Specification |
|
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Aliases | XIAP;API3;BIRC4;IAP3;E3 ubiquitin-protein ligase XIAP;Baculoviral IAP repeat-containing protein 4;IAP-like protein;ILP;hILP;Inhibitor of apoptosis protein 3;IAP-3;hIAP-3;hIAP3;X-linked inhibitor of apoptosis protein;X-linked I |
Conjugation | Unmodified |
Entrez GeneID | 331 |
Swissprot | P98170 |
clone | 2F8C4 |
WB Predicted band size | 57kD |
Host/Isotype | Rabbit IgG,Kappa |
Antibody Type | Primary antibody |
Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
Species Reactivity | Human,Mouse,Rat |
Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
Application |
|
---|---|
WB | 1/2000-1/10000 |
IP | 1/50-1/200 |
ELISA | 1/5000-1/20000 |
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#50940

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