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Confocal Immunofluorescence analysis of methanol-fixed HEK293 cells trasfected with EphB4-hIgGFc using EphB4 mouse mAb (green), showing membrane localization. Blue: DRAQ5 fluorescent DNA dye.

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Mouse Monoclonal Antibody to EPHB4

货号：
20334
别名：
HTK; MYK1; TYRO11
产品上架时间：
2024-01-01
应用：
IF
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P54760
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Mouse Monoclonal Antibody to EPHB4

Description
EphB4: EPH receptor B4, also known as Htk, Myk1, Tyro11. Entrez Protein: NP_004435. It is a member of the Eph receptor family, which bind the ephrin ligand family. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The EphB4 protein binds to ephrin-B2 and plays an essential role in vascular development.

Description

EphB4: EPH receptor B4, also known as Htk, Myk1, Tyro11. Entrez Protein: NP_004435. It is a member of the Eph receptor family, which bind the ephrin ligand family. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The EphB4 protein binds to ephrin-B2 and plays an essential role in vascular development.

References
1. Br J Cancer. 2007 Apr 10;96(7):1083-91. 2. Dig Liver Dis. 2007 Aug;39(8):725-32.

Specification
Aliases	HTK; MYK1; TYRO11
Entrez GeneID	2050
Swissprot	P54760
clone	5B5
WB Predicted band size	108kDa
Host/Isotype	Mouse IgG1
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Purified recombinant extracellular fragment of human EPHB4 fused with hIgGFc tag expressed in HEK293 cell line.
Formulation	Purified antibody in PBS with 0.05% sodium azide.