USP35 (ubiquitin specific peptidase 35) is a 1,017 amino acid protein that belongs to the peptidase C19 family. Expressed in pancreas, testis and skeletal muscle, USP35 functions to catalyze the conversion of a ubiquitin C-terminal thioester and water to free ubiquitin and a thiol, a reaction that may play a role in signaling events throughout the cell.