提醒成功

搜索
Rabbit Polyclonal Antibody to COMT
-
货号:
P02546 -
别名:
HEL-S-98n -
应用:
WB,IHC -
反应种属:
Human -
抗体类型:
Primary antibody -
Swissprot:
P21964 -
规格:
-
数量:
-+ -
说明书:
目录价¥1980

Rabbit Polyclonal Antibody to COMT
Description |
---|
Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters. |
Specification |
|
---|---|
Aliases | HEL-S-98n |
Swissprot | P21964 |
WB Predicted band size | 30 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Fusion protein of human COMT |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
|
---|---|
WB | 1/200-1/1000 |
IHC | 1/20-1/100 |
ELISA | 1/5000-1/10000 |
Product Image
- Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Jurkat and Hela cell lysates, Primary antibody: P02546(COMT Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes
- The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P02546(COMT Antibody) at dilution 1/25. (Original magnification: ×200)
- The image is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using P02546(COMT Antibody) at dilution 1/25. (Original magnification: ×200)
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#P02546

相关产品


