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Western blot analysis using STAT6 mouse mAb against HEK293 (1), NIH/3T3 (2), MCF-7 (3), Raw246.7 (4) and PC-12 (5) cell lysate.
Immunofluorescence analysis of Hela cells using STAT6 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin

Mouse Monoclonal Antibody to STAT6

  • 货号:

    30068
  • 别名:

    STAT6B; STAT6C; D12S1644; IL-4-STAT; STAT6
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IF
  • 反应种属:

    Human,Mouse,Rat,Monkey
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P42226
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to STAT6

Description

STAT6 protein is a transcription factor activated by cytokines, particularly interleukin 4 and IL 13. (STAT6-/-) were found to be deficient in IL 4 mediated functions including Th2 helper T cell differentiation, expression of cell surface markers, T cell proliferation, immunoglobulin class switching to IgE, and partial loss of IL 4 mediated proliferation. STAT6 mRNA has been detected in peripheral bloodlymphocytes, colon, intestine, ovary, prostate,thymus, spleen, kidney, liver, lung and placenta. STAT6 is critically involved in Th2 immune response.

References

1. Pediatr Nephrol. 2009 Mar;24(3):489-95.
2. Mol Immunol. 2009 Jun;46(10):2080-9.
3. Am J Hum Genet. 2009 Nov;85(5):628-42.

Specification

Aliases STAT6B; STAT6C; D12S1644; IL-4-STAT; STAT6
Entrez GeneID 6778
Swissprot P42226
clone 7D3
WB Predicted band size 94kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat,Monkey
Immunogen Purified recombinant fragment of human STAT6 expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500 - 1/2000
IF 1/200 - 1/1000
ELISA 1/10000

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#30068

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