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Rabbit Polyclonal Antibody to UBXN1
-
货号:
P02657 -
别名:
2B28; SAKS1; UBXD10 -
应用:
WB,IHC -
反应种属:
Human, Mouse, Rat -
抗体类型:
Primary antibody -
Swissprot:
Q04323 -
规格:
-
数量:
-+ -
说明书:
目录价¥1980

Rabbit Polyclonal Antibody to UBXN1
Description |
---|
Ubiquitin-binding protein that interacts with the BRCA1-BARD1 heterodimer, and regulates its activity. Specifically binds 'Lys-6'-linked polyubiquitin chains. Interaction with autoubiquitinated BRCA1, leads to inhibit the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer. Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol. |
Specification |
|
---|---|
Aliases | 2B28; SAKS1; UBXD10 |
Swissprot | Q04323 |
WB Predicted band size | 33 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse, Rat |
Immunogen | Full length fusion protein |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
|
---|---|
WB | 1/200-1/1000 |
IHC | 1/25-1/100 |
ELISA | 1/5000-1/10000 |
Product Image
- Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane 1-6: 293T, HEPG2, Hela, LOVO and 231 cell, Mouse brain tissue lysates, Primary antibody: P02657(UBXN1 Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
- The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P02657(UBXN1 Antibody) at dilution 1/20. (Original magnification: ×200)
- The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P02657(UBXN1 Antibody) at dilution 1/20. (Original magnification: ×200)
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#P02657

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