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Immunofluorescence analysis of SK-BR-3 cells using PTH1R mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye.
Immunohistochemical analysis of paraffin-embedded human kidney tissues using PTH1R mouse mAb with DAB staining.

Mouse Monoclonal Antibody to PTH1R

  • 货号:

    30085
  • 别名:

    PFE; PTHR; PTHR1; MGC138426; MGC138452; PTH1R
  • 产品上架时间:

    2024-01-01
  • 应用:

    IHC,IF
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    Q03431
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to PTH1R

Description

The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene.

References

1. Int J Cancer. 2007 Sep 1;121(5):943-54.
2. Mol Endocrinol. 2008 Jan;22(1):156-66.

Specification

Aliases PFE; PTHR; PTHR1; MGC138426; MGC138452; PTH1R
Entrez GeneID 5745
Swissprot Q03431
clone 4D2
WB Predicted band size 66kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human PTH1R expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

IHC 1/200 - 1/1000
IF 1/200 - 1/1000
ELISA 1/10000

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#30085

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