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Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng);
Western blot analysis using CDK9 mouse mAb against Jurkat (1), A431 (2) and HEK293 (3) cell lysate.
Immunohistochemical analysis of paraffin-embedded human endometrial cancer tissues (left) and rectum cancer tissues (right) using CDK9 mouse mAb with DAB staining.

Mouse Monoclonal Antibody to CDK9

  • 货号:

    30212
  • 别名:

    TAK; C-2k; CTK1; CDC2L4; PITALRE
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IHC
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P50750
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to CDK9

Description

The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS. (provided by RefSeq)Tissue specificity: Ubiquitous.

References

1. J Biol Chem. 2008 Mar 21;283(12):7368-78.
2. Mol Cell Biol. 2008 Apr;28(7):2201-12.

Specification

Aliases TAK; C-2k; CTK1; CDC2L4; PITALRE
Entrez GeneID 1025
Swissprot P50750
clone 1B5D10
WB Predicted band size 43kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human CDK9 expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.

Application

WB 1/500 - 1/2000
IHC 1/200 - 1/1000
ELISA 1/10000
XML 地图