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Rabbit Polyclonal Antibody to FOXK1
-
货号:
P10865 -
别名:
FOXK1L -
应用:
WB -
反应种属:
Human, Mouse -
抗体类型:
Primary antibody -
Swissprot:
P85037 -
规格:
-
数量:
-+ -
说明书:
目录价¥1980

Rabbit Polyclonal Antibody to FOXK1
Description |
---|
Transcriptional regulator that binds to the upstream enhancer region (CCAC box) of myoglobin gene. Important regulatory factor of the myogenic progenitor cell population. Involved in the cell cycle process, promotes proliferation by repressing Foxo4 transcriptional activity and the cyclin-dependent kinase inhibitor, p21CIP, in the myogenic progenitor cells. Represses myogenic differentiation by inhibiting MEFC acitivity. Has a role in remodeling processes of adult muscles that occur in response to physiological stimuli. Required to correct temporal orchestration of molecular and cellular events necessary for muscle repair. Positively regulates Wnt/beta-catenin signaling by translocating DVL into the nucleus. Reduces virus replication, probably by binding the interferon stimulated response element (ISRE) to promote antiviral gene expression. |
Specification |
|
---|---|
Aliases | FOXK1L |
Swissprot | P85037 |
WB Predicted band size | 75 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse |
Immunogen | Synthetic peptide of human FOXK1 |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
|
---|---|
WB | 1/500-1/2000 |
ELISA | 1/5000-1/10000 |
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#P10865

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