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Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Western blot analysis using PDE1B mouse mAb against PC-12 (1) cell lysate.
Flow cytometric analysis of A549 cells using PDE1B mouse mAb (green) and negative control (red).
Immunohistochemical analysis of paraffin-embedded human ovarian cancer tissues using PDE1B mouse mAb with DAB staining.
Immunohistochemical analysis of paraffin-embedded human rectum cancer tissues using PDE1B mouse mAb with DAB staining.
Mouse Monoclonal Antibody to PDE1B
-
货号：
30464P -
别名：
PDE1B1; PDES1B -
应用：
WB,IHC,FCM -
反应种属：
Human,Rat -
抗体类型：
Primary antibody -
Swissprot：
Q01064 -
规格：
-
数量：
-+ -
说明书：
目录价¥2180
Mouse Monoclonal Antibody to PDE1B
Description |
|---|
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
References |
|---|
| 1.J Biol Chem. 2007 Nov 9;282(45):32749-57. 2.Proc Natl Acad Sci U S A. 2005 Jan 11;102(2):497-502. |
Specification |
|
|---|---|
| Aliases | PDE1B1; PDES1B |
| Entrez GeneID | 5153 |
| Swissprot | Q01064 |
| clone | 5C4A3 |
| WB Predicted band size | 61.4kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Rat |
| Immunogen | Purified recombinant fragment of human PDE1B (AA: 370-536) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
|
|---|---|
| IHC | 1/200 - 1/1000 |
| FCM | 1/200 - 1/400 |
| ELISA | 1/10000 |
Product Image
- Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
- Western blot analysis using PDE1B mouse mAb against PC-12 (1) cell lysate.
- Flow cytometric analysis of A549 cells using PDE1B mouse mAb (green) and negative control (red).
- Immunohistochemical analysis of paraffin-embedded human ovarian cancer tissues using PDE1B mouse mAb with DAB staining.
- Immunohistochemical analysis of paraffin-embedded human rectum cancer tissues using PDE1B mouse mAb with DAB staining.
For Reseach Only
Application Key：WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#30464P
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